An Association Study of Cervical Cancer Correlated with The Age of Coitarche in Dr. Soetomo Hospital Surabaya
Background: Cervical cancer is one of the deadliest diseases for women’s lives. It is estimated that almost every hour, one died because of cervical cancer and 70% of new cases are found in an advanced stage. Many factors could cause cervical cancer, one of the risk factors is the age of the early coitarche. This study aims to determine the association between the age of coitarche and cervical cancer.
Methods: This study was an analysis of observational study with a case-control design. There were two groups in this study; the case group of outpatients who were diagnosed with cervical cancer and the control group of outpatients who had normal cervical cytology by Papanicolaou screening. The 39 respondents of both the control and case groups, calculated using the Lemeshow’s formula for consecutive sampling, were interviewed for their details concerning reproductive and sexual histories, socio-economic status, hygiene, and education. The independent variable in this study was the age of coitarche; the dependent variable was cervical cancer. The data were analyzed descriptively and using the bivariate analysis (Chi-square) with α=0.05.
Results: It is identified that 39 respondents for each group (case and control) have almost the same percentage of the age of coitarche in One-Stop Oncology Polyclinic (POSA’s outpatient); early coitarche of 43.6% and late coitarche of 56.4%. The age of early coitarche in Obstetrics and Gynecology’s outpatients, as a control group, is rare (4 of 39 respondents; 10.3%) and most of them did their sexual debut at the age of >18 years (89.7%). The chi-square test showed there was a correlation between the age of coitarche and cervical cancer (P=.002; OR=6.76; 95% CI 2.01–22.75).
Conclusions: Early coitarche has a potential effect on cervical cancer.
Torre LA, Islami F, Siegel RL, Ward EM, Jemal A. Global cancer in women: Burden and trends. Cancer Epidemiology Biomarkers and Prevention. 2017 Apr;26(4):444-457.
Vaccarella S, Laversanne M, Ferlay J, Bray F. Cervical cancer in Africa, Latin America and the Caribbean and Asia: Regional inequalities and changing trends. Int J Cancer. 2017 Jul;141:1997-2001.
World Health Organization. Comprehensive cervical cancer control: a guide to essential practice - 2nd ed. WHO Press. 2014.
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. Ca Cancer J Clin. 2018 Sep;68:394-424.
Castellsagué X, Paavonen J, Jaisamrarn U, Wheeler CM, Skinner SR, et al. Risk of first cervical HPV infection and pre-cancerous lesions after onset of sexual activity: analysis of women in the control arm of the randomized, controlled PATRICIA trial. BMC Infect Dis. 2014 Oct;14(551):1-12.
Lubis R, Siregar F, Sanusi S. Pengaruh usia pertama kali melakukan hubungan seksual, paritas, berganti-ganti pasangan seksual, merokok terhadap kejadian Kanker Serviks di RSUD Dr. Pirngadi Medan. Jurnal Muara Sains, Teknologi, Kedokteran, dan Ilmu Kesehatan. 2017 Oct;1(2):145-152.
Rizzo AE, Feldman S. Update on primary HPV screening for cervical cancer prevention. Curr Probl Cancer. 2018 Sep;42(5):507-520.
Rasjidi I. Epidemiologi kanker pada wanita. Sagung Seto. 2010.
Ariani S. Stop kanker. Istana Media. 2015.
Indrawati M. Bahaya kanker bagi wanita dan pria. AV Publisher. 2009.
Kementerian Kesehatan RI. Panduan program nasional gerakan pencegahan dan deteksi dini kanker leher Rahim dan kanker payudara. Direktorat PP dan PTM. 2015.
Liu G, Sharma M, Tan N, Barnabas R. HIV-positive women have higher risk of HPV infection, precancerous lesions, and cervical cancer: A systematic review and meta-analysis. HHS Public Access. 2018 Mar;32(6):795-808.
Makkonen P, Heinävaara S, Sarkeala T, Anttila A. Impact of organized and opportunistic Pap testing on the risk of cervical cancer in young women - A case-control study from Finland. Gynecologic Oncology. 2017 Des;147(3):601-606.
Natalia IW. Strategi komunikasi perwakilan BKKBN Provinsi Jawa Timur dalam mensosialisasikan pemahaman pendewasaan usia perkawinan (PUP) kepada remaja menuju keluarga kecil bahagia sejahtera. 2016 Jun;8(1):847-866.
Latham-Cork H, Porter C, Straw F. Sexual health in young people. Paediatrics and Child Health. 2018 Feb;28(2):93-99.
Yaya S, Bishwajit G. Age at first sexual intercourse and multiple sexual partnerships among women in Nigeria: A cross-sectional analysis. Front Med. 2018 Jun;5(171):1-8.
Diananda R. Panduan lengkap mengenal Kanker. Mirza Media Pustaka. 2009.
Gordon LP, Diaz A, Soghomonian C, Nucci-Sack AT, Weiss JM, et al. Increased body mass index associated with increased risky sexual behaviors. J Pediatr Adollesc Gynecol. 2017 Feb;29(1):42-47.
Montazeri S, Gharacheh M, Mohammadi N, Alaghband RJ, Eftekhar AH. Determinants of early marriage from married girls' perspectives in Iranian setting: a qualitative study. J Environ Public Health. 2016 Mar;2016:1-8.
Bertiani ES. Cara cerdas menghadapi Kanker serviks. Genius Publisher. 2009.
Carcio HA, Secor M. Advanced health assessment of women, fouth edition: clinical skills and procedures. Springer Publishing Company. 2018.
Tapera R, Manyala E, Erick P, Maswabi TM, Tumoyagae T, et al. Knowledge and attitudes towards Cervical Cancer screening amongst University of Botswana Female Students. Asian Pac J Cancer Prev. 2017 ;18(9):2445-2450.
Blödt S, Holmberg C, Müller-Nordhorn J, Rieckmann N. Human Papillomavirus awareness, knowledge and vaccine acceptance: A survey among 18-25 year old male and female vocational school students in Berlin, Germany. Eur J Pub Health. 2012 Dec;22(6):808-813.
Okore O. The use of health promotion to increase the uptake of cervical cancer screening program in Nyangabgwe Hospital, Botswana. University of Limpopo (medunsa Campus). 2011.
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