Parotid Gland Metastasis From Breast Cancer: A Case Report

Bob Andinata, Dewi Iriani, Adlina Karisyah


Introduction: Breast cancer metastasis at the parotid gland is uncommon. There were only 21 cases reported until the recent year, and none of them came from Indonesia. The reports showed that breast cancer metastasis is more often found at the liver, lung, bone, and brain. Therefore, any masses found on the parotid are usually considered as a double primer.

Case Presentation: We report a case of a woman, firstly diagnosed with luminal A stage IIA breast cancer at 39 years old. The patient had undergone breast-conserving therapy (BCT), followed by adjuvant hormonal therapy before being diagnosed with bone metastasis four years later. She also complained about a painful mass on her left upper neck. Ultrasonography and CT-scan resulted in insignificant abnormality. After a year with increasing painful mass, we performed FNAB. The result showed metastatic adenocarcinoma with a suspicious breast cancer origin. We did total parotidectomy with facial nerve preservation to alleviate the pain. Pathology results showed a confirmed diagnosis of breast cancer metastasis. The patient was given radiotherapy as local control and was scheduled to receive chemotherapy as systemic therapy.

Conclusions: Parotid mass with a clinical symptom in the patient with the history of breast cancer should be evaluated firstly by imaging and may be followed by cytology or pathology evaluation to confirm whether it is primary or secondary malignancy. If the parotid metastasis from breast cancer is confirmed, we should consider adding systemic therapy after completing the local control.


Breast cancer, parotid gland, metastasis, systemic therapy, parotidectomy


INFODATIN. Situasi Penyakit Kanker. Jakarta: Kementerian Kesehatan RI, 2015.

Indonesia: Cancer Fact Sheet. United States: International Agency for Research on Cancer, 2018.

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2018;68:394-424.

Mardela AP, Manewat K, Sangchan H. Breast cancer awareness among Indonesian women at moderate-to-high risk. Nurs Health Sci. 2017;19:301-6.

Barsky SH, Gradishar WJ, Recht A, Urist MM. The breast: comprehensive management of benign and malignant disease. Philadelphia: Elsevier Saunders; 2009.

Dixon JM. ABC of breast disease. 3 ed. United Kingdom: Blackwell Publishing; 2006.

Kmeid M, Kamar FG, Nasser S, Moukarzel N. Metachronous, Single Metastasis to the Parotid, from Primary Breast Cancer: A Case Report and Review of the Literature. Case Rep Oncol Med. 2015;2016:1-5.

Cao X-S, Cong B-B, Yu Z-Y. Parotid gland metastasis from carcinoma of the breast detected by PET/CT. Medicine. 2018;97(21):1-4.

Bohli M, Tebra S, Jaffel H, Bouaounia N. Parotid gland metastasis from breast origin. J Clin Case Rep. 2018;8(6):1-3.

Ando K, Masumoto N, Sakamoto M, Teraoka K, Suzukia T, Kurihara T, et al. Parotid Gland Metastasis of Breast Cancer: Case Report and Review of the Literature. Breast Care. 2011;6:471-3.

Khurana R, Azam M. An unusual case of solitary parotid metastasis from early stage breast carcinoma. Clinical Cancer Investigation Journal. 2016;5(3):250-2.

NCCN clinical practice guidelines in oncology: head and neck cancers. Salivary gland tumors. United States: National Comprehensive Cancer Network; 2019.

Alath P, Kapila K, Hussein S, Amanguno H, Hebbar HG, George SS, et al. Parotid gland metastasis of breast cancer diagnosed on fine needle aspiration cytology: case report and review of literature. Cuytopathology. 2014;25(5):346-8.

Kurnia A, Brahma B, Hernowo B, Khambri D, Purwanto DJ, Suprabawati DGA, et al. Panduan petalaksanaan kanker payudara. Jakarta: PERABOI; 2015.

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DOI: 10.33371/ijoc.v14i3.723

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