Management of Cancer Patients during Coronavirus Disease 2019 Pandemic: A Literature Review
Introduction: The number of confirmed cases of Coronavirus Disease 2019 (COVID-19) in the world has been increasing significantly since December 2019. Cancer patients are one of the vulnerable populations to become severe cases of COVID-19 or death when they are contacted with COVID-19. A treatment delay is associated with higher breast cancer-specific mortality and all-cause mortality. However, there is still limited data about how to manage cancer patients in this pandemic of COVID-19. This study aims to appraise the current evidence about the management of cancer patients during the COVID-19 pandemic.
Method: We searched and found 16 articles evaluating the management of cancer patients during the COVID-19 pandemic by searching in PubMed and EMBASE databases. We only included articles discussing COVID-19 and cancer in adults. There were three observational trials, four review articles, two case reports, six letters to the editor, and one guideline.
Results: There were several recommendations regarding patient care in the COVID-19 era. Firstly, outpatient visits, such as follow-up and surveillance of cancer patients, should be postponed. Alternatively, they can do teleconsultation, and their drugs will be delivered to their homes. Stratification and screening for the risk of COVID-19 infection should be done to those who needed urgent or emergency surgery. Otherwise, elective surgery should be postponed. However, several cases can be proceeded after discussion in the Multidisciplinary Team (MDT). Adjuvant and palliative chemotherapy should also be done as scheduled after discussing in MDT. Patients with ongoing radiation treatment should be continued as daily scheduled. Meanwhile, new patients should be carefully evaluated, and those with stable cancer can be postponed for treatment
Conclusions: There is still scarce evidence related to the management of cancer patients during the COVID-19 pandemic. Further studies, in terms of stratification, risk, and management of cancer patients during the pandemic, need to be done to get better evidence on it.
Worldometers. Coronavirus disease 2019 [Internet].
[Updated 2020 April 7th; cited 2020 April 8th].
Available from: https://www.worldometers.info/
World Health Organization. Coronavirus disease 2019 (COVID-19) Situation Report – 70 [Internet]. 2020
[updated 2020 April 7th; cited 2020 April 8th]. Available
Kementerian Kesehatan Republik Indonesia. Info
Infeksi Emerging Kementerian Kesehatan RI [Internet].
[updated 2020 April 7th; cited 2020 April 8th].
Available from: https://covid19.kemkes.go.id/situasiinfeksi-emerging/info-corona-virus/situasi-terkiniperkembangan-coronavirus-covid-19-7-april-2020/#.Xo0DbGVWhOo.
Liang W, Guan W, Chen R. Cancer patients in SARSCoV-2 infection: a nationwide analysis in China.
Lancet Oncol. 2020;21:335–7. Yung R, Ray RM, Roth J, Johnson L, Warnick G, Anderson GL, et al. The association of delay in curative intent treatment with survival among breast cancer patients: Findings from the Women’s Health initiative. Breast cancer Res Treat. 2020;180(3):747–57.
Burki TK. Cancer care in the time of COVID-19. Lancet Oncol. 2020;21(5):628.
Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323(11):1061–69.
Xia Y, Jin R, Zhaot J, Li W, Shen H. Risk of COVID-19
for cancer patients. Lancet Oncol. 2020;21(4):e180.
Suleman K, Almalik O, Haque E, Mushtaq A, Badran
A, Alsayed A, et al. Does the timing of surgery after
neoadjuvant therapy in breast cancer patients affect
the outcome?. Oncology. 2020;98(3):18–73.
Qu J, Yang R, Song L, Kamel IR. Atypical lung feature
on chest CT in a lung adenocarcinoma cancer patient
infected with COVID-19. Ann Oncol. 2020. Jin X, Zheng KI, Pan K, Xie Y, Zheng M. COVID-19 in a patient with chronic lymphocytic leukemia. Lancet Haematol. 2020;7:e351–2
Wang H, Zhang L. Risk of COVID-19 for patients with
cancer. Lancet Oncol. 2020;21(4):e181. Chen N, Zhou M, Dong X. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study. Lancet. 2020;395:507–13.
Souadka A, Benkabbaou A, Ahmadi BA, Boutayeb S,
Majbar MA. Preparing African anticancer centres in
the COVID-19 outbreak. Lancet Oncol. 2020;21(5):e237.
Di Saverio S, Pata F, Gallo G, Carrano F, Scorza A,
Sileri P, et al. Coronavirus pandemic and colorectal
surgery: practical advice based on Italian experience.
Colorectal Dis. 2020;10. Ueda M, Martina R, Hendrie PC, McDonnell T, Crews JR, Wong TL, et al. Managing cancer care during the COVID-19 pandemic: Agility and Collaboration toward a common goal. J Natl Compr Canc Netw. 2020;18(4):1–4.
Fillippi AR, Russi E, Magrini SM, Corvo R. COVID-19
outbreak in northern Italy: first practical indications
for radiotherapy departments. Int J of Radiat Oncol
Biol Phys. 2020. Venderpuye V, Elhassan MMA, Simonds H. Preparedness for COVID-19 in the oncology community in Africa. Lancet Oncol. 2020;21(5):621–
Musseti A, Maluquer C, Albasanz-Puig A, Gudiol C,
Moreno-Gonzales G, Carradini P, et al. Handling the
COVID-19 pandemic in the oncological settings. Lancet Haematol. 2020;7(5):e365–e366. Zhang H, Huang Y, Xie C. The treatment and outcome of a lung cancer patient infected with SARS-COV-2. J Thorac Oncol. 2020;15(5):e63–e64. Yang G, Zhang H, Yang Y. Challenges and countermeasures of Integrative cancer therapy in the Epidemic of COVID-19. Integr Cancer Ther. 2020;19:1–2.
General office of the national health commission of
China, general office of the State administration of
traditional Chinese Medicine. Diagnosis and treatment
protocol for 2019-nCoV (Sixth Trial Edition) [Internet].
[updated 2020 February 19th; cited 2020 February 28th]. Available from: http://www.nhc.gov.
d7da8aefc2.shtml. Zhou FYT, Du R, Fan G. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study. Lancet. 2020;395(10229):1054–62.
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